製品の概要

  • 製品名Anti-SLC27A5 antibody
    SLC27A5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SLC27A5
  • アプリケーション適用あり: WB, ELISA, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of human SLC27A5

  • ポジティブ・コントロール
    • IHC-P: human liver carcinoma tissue. WB: extracts from HepG2 cells. ICC/IF: A549 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab74869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 75 kDa.
ELISA 1/40000.
IHC-P Use at an assay dependent concentration.
ICC/IF 1/500 - 1/1000.

ターゲット情報

  • 機能Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.
  • 組織特異性Predominantly expressed in liver.
  • 配列類似性Belongs to the ATP-dependent AMP-binding enzyme family.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ACSB antibody
    • ACSVL6 antibody
    • BA CoA ligase antibody
    • BA-CoA ligase antibody
    • BACS antibody
    • BAL antibody
    • Bile acid CoA ligase antibody
    • Bile acid-CoA ligase antibody
    • Bile acyl CoA synthetase antibody
    • Bile acyl-CoA synthetase antibody
    • Cholate CoA ligase antibody
    • Cholate--CoA ligase antibody
    • FACVL3 antibody
    • FATP 5 antibody
    • FATP-5 antibody
    • FATP5 antibody
    • Fatty acid Coenzyme A ligase very long chain 3 antibody
    • Fatty acid transport protein 5 antibody
    • Fatty-acid-coenzyme A ligase antibody
    • FLJ22987 antibody
    • S27A5_HUMAN antibody
    • Slc27a5 antibody
    • Solute carrier family 27 (fatty acid transporter) member 5 antibody
    • Solute carrier family 27 member 5 antibody
    • Very long chain acyl CoA synthetase homolog 2 antibody
    • Very long chain acyl CoA synthetase related protein antibody
    • very long-chain 3 antibody
    • Very long-chain acyl-CoA synthetase homolog 2 antibody
    • Very long-chain acyl-CoA synthetase-related protein antibody
    • VLACS related antibody
    • VLACS-related antibody
    • VLACSR antibody
    • VLCS H2 antibody
    • VLCS-H2 antibody
    • VLCSH2 antibody
    see all

Anti-SLC27A5 antibody 画像

  • Immunohistochemistry analysis of SLC27A5 in paraffin-embedded human liver carcinoma tissue using ab74869, at 1/50 dilution, in the presence (right panel) or absence (left panel) of immunising peptide.
  • All lanes : Anti-SLC27A5 antibody (ab74869) at 1/500 dilution

    Lane 1 : Extracts from HepG2 cells
    Lane 2 : Extracts from HepG2 cells with immunising peptide at 5 µg

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 75 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)
  • Immunofluorescence analysis of SLC27A5 in A549 cells, using ab74869, at 1/500 dilution, in the presence (right panel) or absence (left panel) of immunising peptide.

Anti-SLC27A5 antibody (ab74869) 使用論文

ab74869 has not yet been referenced specifically in any publications.

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Thank you very much for your call yesterday and for your interest in ab74869.

I've heard back from the lab, and unfortunately the immunogen of this antibody only shares 57% identity with the mouse sequence, so it's not highly likely to cross-...

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