The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa.
Use a concentration of 10 µg/ml.
Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+).
Defects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD) [MIM:610773]. MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life.
Belongs to the mitochondrial carrier family. Contains 3 Solcar repeats.