製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SLC25A12
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids 1-30 of Human SLC25A12 (NP_003696.2)

  • ポジティブ・コントロール
    • Mouse bladder tissue lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107436 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 75 kDa.

ターゲット情報

  • 機能
    Calcium-dependent mitochondrial aspartate and glutamate carrier. May have a function in the urea cycle.
  • 組織特異性
    High levels in heart and skeletal muscle, low in brain and very low in kidney.
  • 関連疾患
    Defects in SLC25A12 are the cause of aspartate-glutamate carrier 1 deficiency (AGC1D) [MIM:612949]; also called global cerebral hypomyelination. This syndrome consists of a child severe psychomotor retardation, hypotonia and hypomyelination of the central nervous system.
  • 配列類似性
    Belongs to the mitochondrial carrier family.
    Contains 4 EF-hand domains.
    Contains 3 Solcar repeats.
  • 細胞内局在
    Mitochondrion inner membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AGC1 antibody
    • Araceli hiperlarga antibody
    • ARALAR antibody
    • ARALAR1 antibody
    • Calcium binding mitochondrial carrier superfamily member antibody
    • Calcium binding mitochondrial carrier superfamily member Aralar1 antibody
    • Calcium-binding mitochondrial carrier protein Aralar1 antibody
    • CMC1_HUMAN antibody
    • Mitochondrial aspartate glutamate carrier 1 antibody
    • SLC25A12 antibody
    • Solute carrier family 25 (aspartate/glutamate carrier) member 12 antibody
    • Solute carrier family 25 (mitochondrial carrier Aralar) member 12 antibody
    • Solute carrier family 25 member 12 antibody
    • solute carrier family 25, member 12 antibody
    see all

画像

  • Anti-SLC25A12 antibody (ab107436) at 1/100 dilution + Mouse bladder tissue lysates at 35 µg

    Predicted band size : 75 kDa

プロトコール

参考文献

ab107436 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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