製品の概要

  • 製品名Anti-SLC22A8 antibody
    SLC22A8 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to SLC22A8
  • 特異性This antibody is reactive against mammalian transfected lysate.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    SLC22A8 (NP_004245, 1 a.a. ~ 542 a.a) human protein.

  • ポジティブ・コントロール
    • Transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab69883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 60 kDa).

ターゲット情報

  • 機能Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
  • 組織特異性Expressed in kidney.
  • 配列類似性Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
  • 細胞内局在Basolateral cell membrane. Localizes on the brush border membrane of the choroid epithelial cells. Localizes to the basolateral membrane of the proximal tubular cells. Localizes on the abluminal and possibly, luminal membrane of the brain capillary endothelial cells (BCEC) (By similarity).
  • Information by UniProt
  • 参照データベース
  • 別名
    • hOAT3 antibody
    • OAT3 antibody
    • Organic anion transporter 3 antibody
    • S22A8_HUMAN antibody
    • SLC22A8 antibody
    • Solute carrier family 22 (organic anion transporter), member 8 antibody
    • Solute carrier family 22 member 8 antibody
    see all

Anti-SLC22A8 antibody 画像

  • All lanes : Anti-SLC22A8 antibody (ab69883) at 1/500 dilution

    Lane 1 : SLC22A8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 60 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

Anti-SLC22A8 antibody (ab69883) 使用論文

This product has been referenced in:
  • Kunin M  et al. Urinary organic anion transporter protein profiles in AKI. Nephrol Dial Transplant 27:1387-95 (2012). WB ; Human . Read more (PubMed: 21945944) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"