製品の概要

  • 製品名
    Anti-SLC22A11 antibody
  • 製品の詳細
    Rabbit polyclonal to SLC22A11
  • アプリケーション
    適用あり: WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to a region of Human SLC22A11

  • ポジティブ・コントロール
    • Human Fetal liver lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab76385 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 60 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/312500.

ICC/IF Use at an assay dependent concentration. PubMed: 23516613

ターゲット情報

  • 関連性
    SLC22A11 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. It is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. SLC22A11 mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.
  • 細胞内局在
    Cell membrane; Multi-pass membrane protein.
  • 参照データベース
  • 別名
    • hOAT4 antibody
    • MGC34282 antibody
    • OAT4 antibody
    • Organic anion transporter 4 antibody
    • Solute carrier family 22 (organic anion/urate transporter) member 11 antibody
    • Solute carrier family 22 member 11 antibody
    see all

画像

  • Anti-SLC22A11 antibody (ab76385) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal liver lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 60 kDa
    Observed band size : 60 kDa

参考文献

This product has been referenced in:
  • DesRochers TM  et al. Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity. PLoS One 8:e59219 (2013). IHC-P, ICC/IF ; Human . Read more (PubMed: 23516613) »
  • Woo CS  et al. Fate of the teratogenic and carcinogenic ochratoxin A in human perfused placenta. Toxicol Lett 208:92-9 (2012). WB ; Human . Read more (PubMed: 22037670) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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