製品の概要

  • 製品名Anti-SLC12A4 antibody
    SLC12A4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SLC12A4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MPHFTVVPVD GPRRGDYDNL EGLSWVDYGE RAELDDSDGH GNHRESSPFL) of Human SLC12A4 (NP_005063).

  • ポジティブ・コントロール
    • PANC1 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab99053 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 121 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.
  • 組織特異性Ubiquitous. Levels are much higher in erythrocytes from patients with Hb SC and Hb SS compared to normal AA erythrocytes. This may contribute to red blood cell dehydration and to the manifestation of sickle cell disease by increasing the intracellular concentration of HbS. Isoform 1 was not detected in circulating reticulocytes.
  • 配列類似性Belongs to the SLC12A transporter family.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Electroneutral potassium chloride cotransporter 1 antibody
    • Electroneutral potassium-chloride cotransporter 1 antibody
    • Erythroid K Cl cotransporter 1 antibody
    • Erythroid K-Cl cotransporter 1 antibody
    • FLJ40489 antibody
    • hKCC 1 antibody
    • hKCC1 antibody
    • KCC 1 antibody
    • KCC1 antibody
    • Potassium transport protein antibody
    • Potassium/chloride cotransporter 1 antibody
    • S12A4_HUMAN antibody
    • Slc12a4 antibody
    • Solute carrier family 12 (potassium/chloride transporters) member 4 antibody
    • Solute carrier family 12 member 4 antibody
    see all

Anti-SLC12A4 antibody 画像

  • Anti-SLC12A4 antibody (ab99053) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 121 kDa

Anti-SLC12A4 antibody (ab99053) 使用論文

ab99053 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab99053.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"