製品の概要

  • 製品名Anti-SLC12A4 antibody
    SLC12A4 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to SLC12A4
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Cow, Dog, Pig, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-DPSHAPDNFRE

    , corresponding to internal sequence amino acids 995-1005 of Human SLC12A4 (NP_005063.1).

  • ポジティブ・コントロール
    • Human Heart and Muscle lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99% Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab77340 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunising peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報Peptide ELISA: Antibody detection limit dilution 1/4000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 150 kDa (predicted molecular weight: 121 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.
    • 組織特異性Ubiquitous. Levels are much higher in erythrocytes from patients with Hb SC and Hb SS compared to normal AA erythrocytes. This may contribute to red blood cell dehydration and to the manifestation of sickle cell disease by increasing the intracellular concentration of HbS. Isoform 1 was not detected in circulating reticulocytes.
    • 配列類似性Belongs to the SLC12A transporter family.
    • 翻訳後修飾N-glycosylated.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Electroneutral potassium chloride cotransporter 1 antibody
      • Electroneutral potassium-chloride cotransporter 1 antibody
      • Erythroid K Cl cotransporter 1 antibody
      • Erythroid K-Cl cotransporter 1 antibody
      • FLJ40489 antibody
      • hKCC 1 antibody
      • hKCC1 antibody
      • KCC 1 antibody
      • KCC1 antibody
      • Potassium transport protein antibody
      • Potassium/chloride cotransporter 1 antibody
      • S12A4_HUMAN antibody
      • Slc12a4 antibody
      • Solute carrier family 12 (potassium/chloride transporters) member 4 antibody
      • Solute carrier family 12 member 4 antibody
      see all

    Anti-SLC12A4 antibody 画像

    Anti-SLC12A4 antibody (ab77340) 使用論文

    ab77340 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab77340.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"