製品の概要

  • 製品名Anti-SLC12A4 antibody
    SLC12A4 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SLC12A4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-110 of Human SLC12A4

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab58163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.
    • 組織特異性Ubiquitous. Levels are much higher in erythrocytes from patients with Hb SC and Hb SS compared to normal AA erythrocytes. This may contribute to red blood cell dehydration and to the manifestation of sickle cell disease by increasing the intracellular concentration of HbS. Isoform 1 was not detected in circulating reticulocytes.
    • 配列類似性Belongs to the SLC12A transporter family.
    • 翻訳後修飾N-glycosylated.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Electroneutral potassium chloride cotransporter 1 antibody
      • Electroneutral potassium-chloride cotransporter 1 antibody
      • Erythroid K Cl cotransporter 1 antibody
      • Erythroid K-Cl cotransporter 1 antibody
      • FLJ40489 antibody
      • hKCC 1 antibody
      • hKCC1 antibody
      • KCC 1 antibody
      • KCC1 antibody
      • Potassium transport protein antibody
      • Potassium/chloride cotransporter 1 antibody
      • S12A4_HUMAN antibody
      • Slc12a4 antibody
      • Solute carrier family 12 (potassium/chloride transporters) member 4 antibody
      • Solute carrier family 12 member 4 antibody
      see all

    Anti-SLC12A4 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab58163 SLC12A4 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-SLC12A4 antibody (ab58163) 使用論文

    ab58163 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab58163.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"