製品の概要

  • 製品名Anti-Slap antibody
    Slap 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Slap
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1-248 of Human Slap (AAH07042).

  • ポジティブ・コントロール
    • 293T and A431 cell lysates

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab96620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 31 kDa.

ターゲット情報

  • 機能Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
  • 組織特異性Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.
  • 配列類似性Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • ドメインThe C-terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization.
  • 細胞内局在Cytoplasm. Endosome. Colocalizes with endosomes.
  • Information by UniProt
  • 参照データベース
  • 別名
    • hSLAP antibody
    • SLA 1 antibody
    • sla antibody
    • SLA1 antibody
    • SLAP 1 antibody
    • SLAP antibody
    • SLAP-1 antibody
    • SLAP1 antibody
    • SLAP1_HUMAN antibody
    • Src like adapter antibody
    • Src like adapter protein 1 antibody
    • Src like adaptor antibody
    • SRC-like-adapter antibody
    • Src-like-adapter protein 1 antibody
    see all

Anti-Slap antibody 画像

  • All lanes : Anti-Slap antibody (ab96620) at 1/2000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 31 kDa

Anti-Slap antibody (ab96620) 使用論文

ab96620 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96620.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"