製品の概要

  • 製品名SKF 97541
  • 製品の詳細
    Highly potent GABAB agonist
  • 別名
    • CGP 35024
  • 生理活性の詳細Highly potent GABAB agonist, 10-fold more potent than Baclofen (ab120149). (EC50 values for depression of striatal synaptic potentials are 920 nM and 1.25 μM for SKF97541 and baclofen, respectively).

    Also available in simple stock solutions (ab146688) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度> 98%

製品の特性

    関連製品

    SKF 97541 (ab120250) 使用論文

    This product has been referenced in:
    • Mares P Anticonvulsant action of GABA-B receptor agonist SKF97541 differs from that of baclofen. Physiol Res 57:789-92 (2008). Read more (PubMed: 17949247) »
    • Bräuner-Osborne H & Krogsgaard-Larsen P Functional pharmacology of cloned heterodimeric GABAB receptors expressed in mammalian cells. Br J Pharmacol 128:1370-4 (1999). Read more (PubMed: 10602314) »
    • Seabrook GR  et al. Electrophysiological characterization of potent agonists and antagonists at pre- and postsynaptic GABAB receptors on neurones in rat brain slices. Br J Pharmacol 101:949-57 (1990). Read more (PubMed: 1964824) »

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