製品の概要

  • 製品名Anti-SKA2 antibody
    SKA2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SKA2
  • 特異性This antibody is specific for SKA2 and will not crossreact with SKA1 or SKA3.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A 15 amino acid peptide from near the N terminus of Human SKA2 (NP_872426).

  • ポジティブ・コントロール
    • 3T3 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Affinity chromatography purified via peptide column
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab91551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 14 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.
    • 配列類似性Belongs to the SKA2 family.
    • 細胞内局在Cytoplasm > cytoskeleton > spindle. Chromosome > centromere > kinetochore. Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FAM33A antibody
      • Family with sequence similarity 33, member A antibody
      • FLJ12758 antibody
      • MGC110975 antibody
      • Protein FAM33A antibody
      • SKA 2 antibody
      • SKA2 antibody
      • SKA2_HUMAN antibody
      • Spindle and kinetochore associated complex subunit 2 antibody
      • Spindle and kinetochore associated protein 2 antibody
      • Spindle and kinetochore-associated protein 2 antibody
      • Spindle and KT (kinetochore) associated 2 antibody
      • Spindle and KT associated 2 antibody
      see all

    Anti-SKA2 antibody 画像

    • Lane 1 : Anti-SKA2 antibody (ab91551) at 0.5 µg/ml
      Lane 2 : Anti-SKA2 antibody (ab91551) at 1 µg/ml

      Lane 1 : 3T3 cell lysate
      Lane 2 : 3T3 cell lysate

      Lysates/proteins at 15 µg per lane.


      Predicted band size : 14 kDa

    Anti-SKA2 antibody (ab91551) 使用論文

    ab91551 has not yet been referenced specifically in any publications.

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