Anti-SIX2 抗体 [EPR4824] (ab111827)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4824] to SIX2
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
製品の概要
-
製品名
Anti-SIX2 antibody [EPR4824]
SIX2 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR4824] to SIX2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
ポジティブ・コントロール
- Skeletal Muscle (Rat) Nuclear Lysate - normal tissue (ab29375) can be used as a positive control in WB. Human, Mouse and Rat skeletal muscle lysates; L6 lysate
-
特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR4824 -
アイソタイプ
IgG -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab111827の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 32 kDa.
|
特記事項 |
---|
WB
1/1000 - 1/10000. Predicted molecular weight: 32 kDa. |
ターゲット情報
-
機能
May be involved in limb tendon and ligament development. -
組織特異性
Strongly expressed in skeletal muscle. -
配列類似性
Belongs to the SIX/Sine oculis homeobox family.
Contains 1 homeobox DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
-
参照データベース
- Entrez Gene: 10736 Human
- Entrez Gene: 20472 Mouse
- Entrez Gene: 366542 Rat
- Omim: 604994 Human
- SwissProt: Q9NPC8 Human
- SwissProt: Q62232 Mouse
- Unigene: 101937 Human
- Unigene: 5039 Mouse
-
別名
- Homeobox protein SIX2 antibody
- OTTHUMP00000201649 antibody
- Sine oculis homeobox (Drosophila) homolog 2 antibody
see all
画像
-
All lanes : Anti-SIX2 antibody [EPR4824] (ab111827) at 1/1000 dilution
Lane 1 : Human skeletal muscle lysate
Lane 2 : Mouse skeletal muscle lysate
Lane 3 : Rat skeletal muscle lysate
Lane 4 : L6 lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 32 kDa
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (2)
ab111827 は 2 報の論文で使用されています。
- Creed TM et al. The PAX-SIX-EYA-DACH network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis. Development 147:N/A (2020). PubMed: 31806659
- Jia Q et al. Circular RNA 0007255 regulates the progression of breast cancer through miR-335-5p/SIX2 axis. Thorac Cancer 11:619-630 (2020). PubMed: 31962380