Mouse monoclonal [SIT-01] to SIT (Phycoerythrin)
Phycoerythrin. Ex: 488nm, Em: 575nm
ab36418 reacts with SIT.
Recombinant fragment (Human)
Bacterially produced recombinant intracellular fragment of human SIT.
Shipped at 4°C. Store at +4°C.
Preservative: 15mM Sodium Azide
Constituents: 0.2% BSA, PBS
Concentration information loading...
The conjugate was purified by size-exclusion chromatography
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma.
Phosphorylated on tyrosines by LCK, FYN or ZAP70 upon TCR activation; which leads to the recruitment of PTPN11, GRB2 and CSK.
Information by UniProt
- gp30/40 antibody
- SHP intracting transmembrane adapter protein antibody
- SHP2-interacting transmembrane adapter protein antibody
has not yet been referenced specifically in any publications.
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