製品の概要

  • 製品名Anti-SIRT2 antibody
    SIRT2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SIRT2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: YTQNIDTLER IAGLEQEDLV EAHGTFYTSH CVSASCRHEY PLSWMKEKIF SEVTPKCEDC QSLVKPDIVF FGESLPARFF SCMQSDFLKV DLLLVMGTSL , corresponding to amino acids 128-227 of Human SIR2/ SIRT2

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.
    • 組織特異性Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.
    • 配列類似性Belongs to the sirtuin family.
      Contains 1 deacetylase sirtuin-type domain.
    • 発生段階Peaks during mitosis. After mitosis, it is probably degraded by the 26S proteasome.
    • 翻訳後修飾Phosphorylated at the G2/M transition of the cell cycle.
    • 細胞内局在Cytoplasm > cytoskeleton. Colocalizes with microtubules.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FLJ35621 antibody
      • FLJ37491 antibody
      • NAD dependent deacetylase sirtuin 2 antibody
      • NAD-dependent deacetylase sirtuin-2 antibody
      • NAD-dependent protein deacetylase sirtuin-2 antibody
      • Regulatory protein SIR2 homolog 2 antibody
      • Silencing information regulator 2 like antibody
      • Silent information regulator 2 antibody
      • SIR2 antibody
      • SIR2 like protein 2 antibody
      • Sir2 related protein type 2 antibody
      • SIR2, S. cerevisiae, homolog-loke 2 antibody
      • SIR2-like protein 2 antibody
      • SIR2L antibody
      • SIR2L2 antibody
      • SIRT2 antibody
      • SIRT2_HUMAN antibody
      • Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae) antibody
      • Sirtuin 2 antibody
      • Sirtuin type 2 antibody
      see all

    Anti-SIRT2 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab56904 SIR2 / SIRT2 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    Anti-SIRT2 antibody (ab56904) 使用論文

    ab56904 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56904.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"