Anti-SIRP alpha 抗体 [OX-41] (FITC) (ab34076)


  • 製品名
    Anti-SIRP alpha antibody [OX-41] (FITC)
    SIRP alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [OX-41] to SIRP alpha (FITC)
  • 由来種
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Peritoneal macrophages (Rat)

  • エピトープ
    ab34076 binds to a different epitope on SIRP than ab34079, ab34081 and ab34086.



Our Abpromise guarantee covers the use of ab34076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報
    Flow Cyt: Use at an assay dependent dilution. Use 10µl dilution for 106 cells in 100ul.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
    • 組織特異性
      Ubiquitous. Highly expressed in brain. Detected on myeloid cells, but not T-cells. Detected at lower levels in heart, placenta, lung, testis, ovary, colon, liver, small intestine, prostate, spleen, kidney, skeletal muscle and pancreas.
    • 配列類似性
      Contains 2 Ig-like C1-type (immunoglobulin-like) domains.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • 翻訳後修飾
      Phosphorylated on tyrosine residues in response to stimulation with EGF, growth hormone, insulin and PDGF. Dephosphorylated by PTPN11.
    • 細胞内局在
    • Information by UniProt
    • 参照データベース
    • 別名
      • Signal regulatory protein alpha type 1 antibody
      • Bit antibody
      • Brain Ig like molecule with tyrosine based activation motifs antibody
      • Brain Ig-like molecule with tyrosine-based activation motifs antibody
      • Brain immunoglobulin like molecule with tyrosine based activation motifs antibody
      • CD172 antigen like family member A antibody
      • CD172 antigen-like family member A antibody
      • CD172a antibody
      • CD172a antigen antibody
      • Inhibitory receptor SHPS-1 antibody
      • Macrophage fusion receptor antibody
      • MFR antibody
      • MYD 1 antibody
      • Myd 1 antigen antibody
      • MyD-1 antigen antibody
      • p84 antibody
      • Protein tyrosine phosphatase non receptor type substrate 1 antibody
      • PTPNS1 antibody
      • SHP substrate 1 antibody
      • SHPS-1 antibody
      • SHPS1 antibody
      • SHPS1_HUMAN antibody
      • Signal regulatory protein alpha 2 antibody
      • Signal regulatory protein alpha 3 antibody
      • Signal regulatory protein alpha antibody
      • Signal regulatory protein alpha type 2 antibody
      • Signal-regulatory protein alpha-1 antibody
      • Signal-regulatory protein alpha-2 antibody
      • Signal-regulatory protein alpha-3 antibody
      • SIRP antibody
      • Sirp-alpha-1 antibody
      • Sirp-alpha-2 antibody
      • Sirp-alpha-3 antibody
      • SIRPA antibody
      • SIRPalpha antibody
      • SIRPalpha1 antibody
      • SIRPalpha2 antibody
      • SIRPalpha3 antibody
      • Tyrosine phosphatase SHP substrate 1 antibody
      • Tyrosine protein phosphatase non receptor type substrate 1 antibody
      • Tyrosine-protein phosphatase non-receptor type substrate 1 antibody
      see all



    ab34076 has not yet been referenced specifically in any publications.

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