製品の概要
-
製品名Anti-Sin3b antibody
Sin3b 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to Sin3b
-
由来種Rabbit
-
アプリケーション適用あり: WBmore details
-
種交差性交差種: Human
交差が予測される動物種: Mouse, Rat
-
免疫原
Recombinant fragment, corresponding to a region within amino acids 15-215 of Human Sin3b.
-
ポジティブ･コントロール
- HepG2 cell line and HCT116 whole cell lysate
法規制情報
製品の特性
-
製品の状態Liquid
-
保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
-
バッファーPreservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0 -
Concentration information loading... -
精製度Immunogen affinity purified
-
ポリ/モノポリクローナル
-
アイソタイプIgG
-
研究分野
関連製品
-
Compatible Secondaries
-
Positive Controls
アプリケーション
Our Abpromise guarantee covers the use of ab101843 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 133 kDa. |
ターゲット情報
-
関連性Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
-
細胞内局在Nuclear
-
参照データベース
- Entrez Gene: 23309 Human
- Entrez Gene: 20467 Mouse
- Entrez Gene: 683381 Rat
- Omim: 607777 Human
- SwissProt: O75182 Human
- SwissProt: Q62141 Mouse
- SwissProt: Q3B8P8 Rat
- Unigene: 13999 Human
-
別名
- Histone deacetylase complex subunit Sin3b antibody
- Paired amphipathic helix protein Sin3b antibody
- SIN3 homolog B transcription regulator antibody
see all
画像
-
Western blot - Anti-Sin3b antibody (ab101843)Anti-Sin3b antibody (ab101843) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg
Predicted band size: 133 kDa
10% SDS PAGE
プロトコール
参考文献
ab101843 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"