製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Sin3b
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 15-215 of Human Sin3b.

  • ポジティブ・コントロール
    • HepG2 cell line and HCT116 whole cell lysate

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab101843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 133 kDa.

ターゲット情報

  • 関連性
    Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
  • 細胞内局在
    Nuclear
  • 参照データベース
  • 別名
    • Histone deacetylase complex subunit Sin3b antibody
    • Paired amphipathic helix protein Sin3b antibody
    • SIN3 homolog B transcription regulator antibody
    • SIN3 transcription regulator family member B antibody
    • SIN3 transcription regulator homolog B antibody
    • Transcriptional corepressor Sin3b antibody
    see all

画像

  • Anti-Sin3b antibody (ab101843) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 133 kDa

プロトコール

参考文献

ab101843 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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