Anti-Sin3b 抗体 (ab101843)

製品の概要

• 製品名
  Anti-Sin3b antibody
  Sin3b 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to Sin3b
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Human
  交差が予測される動物種: Mouse, Rat
• 免疫原

  Recombinant fragment, corresponding to a region within amino acids 15-215 of Human Sin3b.

• ポジティブ･コントロール
  • HepG2 cell line and HCT116 whole cell lysate

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• バッファー
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Other factors

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Co-factors

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipid metabolism

  • Metabolism
  • Pathways and Processes
  • Cofactors, Vitamins / minerals
  • Co-factors

  • Metabolism
  • Types of disease
  • Cancer

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • HepG2 nuclear extract lysate (ab14660)

アプリケーション

ターゲット情報

• 関連性
  Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
• 細胞内局在
  Nuclear
• 参照データベース
  • Entrez Gene: 23309 Human
  • Entrez Gene: 20467 Mouse
  • Entrez Gene: 683381 Rat
  • Omim: 607777 Human
  • SwissProt: O75182 Human
  • SwissProt: Q62141 Mouse
  • SwissProt: Q3B8P8 Rat
  • Unigene: 13999 Human
• 別名
  • Histone deacetylase complex subunit Sin3b antibody
  • Paired amphipathic helix protein Sin3b antibody
  • SIN3 homolog B transcription regulator antibody

  • SIN3 transcription regulator family member B antibody
  • SIN3 transcription regulator homolog B antibody
  • Transcriptional corepressor Sin3b antibody

  see all

プロトコール

• Western blot protocols