Anti-Silencer of Death Domain 抗体 [EPR3596] (ab108988)

製品の概要

  • 製品名Anti-Silencer of Death Domain antibody [EPR3596]
    Silencer of Death Domain 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR3596] to Silencer of Death Domain
  • アプリケーション適用あり: WB, Flow Cyt, ICC/IFmore details
    適用なし: IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human Silencer of Death Domain (UniProt O95429).

  • ポジティブ・コントロール
    • WB: HeLa, HepG2, and Molt-4 cell lysates ICC/IF: HeLa cells
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab108988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 65 kDa (predicted molecular weight: 50 kDa).
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF 1/100 - 1/250.
  • 追加情報Is unsuitable for IHC-P or IP.
  • ターゲット情報

    • 機能Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
    • 組織特異性Ubiquitous.
    • 配列類似性Contains 1 BAG domain.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BAG 4 antibody
      • BAG family molecular chaperone regulator 4 antibody
      • BAG-4 antibody
      • BAG4 antibody
      • BAG4_HUMAN antibody
      • Bcl 2 associated athanogene 4 antibody
      • Bcl-2-associated athanogene 4 antibody
      • BCL2 associated athanogene 4 antibody
      • Silencer of death domains antibody
      • SODD antibody
      see all

    Anti-Silencer of Death Domain antibody [EPR3596] 画像

    • All lanes : Anti-Silencer of Death Domain antibody [EPR3596] (ab108988) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : Molt-4 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit IgG at 1/2000 dilution

      Predicted band size : 50 kDa
      Observed band size : 65 kDa (why is the actual band size different from the predicted?)
    • Immunofluorescent staining of Silencer of Death Domain in HeLa cells, using ab108988 at a 1/100 dilution.

    Anti-Silencer of Death Domain antibody [EPR3596] (ab108988) 使用論文

    ab108988 has not yet been referenced specifically in any publications.

    Product Wall

    The Anti-Silencer of Death Domain antibody ab108988 is unlikely to react with the sequence you provided. The immunogen for the antibody is a 15 amino acid peptide and alignment with your sequence returns only 4 matching amino acids, PPQ-P.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"