Anti-SIK3 抗体 (ab110987)
Key features and details
- Rabbit polyclonal to SIK3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SIK3 antibody
SIK3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SIK3 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Synthetic peptide derived from an internal sequence of Human SIK3.
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ポジティブ・コントロール
- Human lung carcinoma tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS (without Mg2+ and Ca2+) -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab110987 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab110987の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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配列類似性
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Contains 1 protein kinase domain.
Contains 1 UBA domain. -
翻訳後修飾
Phosphorylated at Thr-163 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. -
細胞内局在
Cytoplasm. Locates to punctate structures within the cytoplasm on binding to YWHAZ. - Information by UniProt
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参照データベース
- Entrez Gene: 23387 Human
- Entrez Gene: 70661 Mouse
- Omim: 614776 Human
- SwissProt: Q9Y2K2 Human
- SwissProt: Q6P4S6 Mouse
- Unigene: 167451 Human
- Unigene: 219459 Mouse
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別名
- FLJ12240 antibody
- KIAA0999 antibody
- L19 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab110987 は 2 報の論文で使用されています。
- Murray CW et al. An LKB1-SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation. Cancer Discov 9:1590-1605 (2019). PubMed: 31350327
- Wolber LE et al. Salt-inducible kinase 3, SIK3, is a new gene associated with hearing. Hum Mol Genet N/A:N/A (2014). IHC-P, IHC (PFA fixed) ; Mouse . PubMed: 25060954