Anti-Signal peptide peptidase-like 2B 抗体 (ab43856)

製品の概要

  • 製品名Anti-Signal peptide peptidase-like 2B antibody
    Signal peptide peptidase-like 2B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Signal peptide peptidase-like 2B
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Signal peptide peptidase-like 2B.

    (Peptide available as ab43855.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in WI38 Whole Cell Lysate, Human Thymus Tissue Lysate and Human Brain Tissue Lysate (data not shown).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab43856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 65 kDa).

ターゲット情報

  • 関連性The SPPLs are a group of aspartic proteases that are responsible for proteolysis of type II membrane-anchored signalling factors. SPPL2b, unlike other SPPL family members is found in endosomes/lysosomes, and not the endoplasmic reticulum, and has a role in catalysing intramembrane cleavage of tumour necrosis factor alpha (TNFalpha).
  • 細胞内局在Membrane; multi-pass membrane protein of endosomes/lysosomes.
  • 参照データベース
  • 別名
    • IMP4 antibody
    • Intramembrane protease 4 antibody
    • Protein SPP-like 2B antibody
    • SPPL2B antibody

Anti-Signal peptide peptidase-like 2B antibody 画像

  • All lanes : Anti-Signal peptide peptidase-like 2B antibody (ab43856) at 1 µg/ml

    Lane 1 : WI-38 whole cell lysate (ab3960)
    Lane 2 : Human thymus tissue lysate - total protein (ab30146)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Performed under reducing conditions.

    Predicted band size : 65 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-Signal peptide peptidase-like 2B antibody (ab43856) 使用論文

ab43856 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"