Anti-Signal Peptide Peptidase 抗体 (ab113872)

製品の概要

  • 製品名Anti-Signal Peptide Peptidase antibody
    Signal Peptide Peptidase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Signal Peptide Peptidase
  • 特異性ab113872 will recognise isoform 1, 3 and 4 UniProt ID Q9D8V0
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 240-289 (IKLVFPQDLL EKGLEADNFA MLGLGDIVIP GIFIALLLRF DISLKKNTHT) of Mouse Signal Peptide Peptidase (Q9D8V0 isoform 1).

  • ポジティブ・コントロール
    • Mouse Spleen lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection (By similarity). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein. Involved in the intramembrane cleavage of the integral membrane protein PSEN1.
  • 組織特異性Widely expressed with highest levels in kidney, liver, placenta, lung, leukocytes and small intestine and reduced expression in heart and skeletal muscle. Expressed abundantly in the CNS with highest levels in thalamus and medulla.
  • 配列類似性Belongs to the peptidase A22B family.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Cell membrane and Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • dJ324O17.1 antibody
    • H13 antibody
    • hIMP1 antibody
    • Histocompatibility (minor) 13 antibody
    • HM13 antibody
    • HM13_HUMAN antibody
    • IMP-1 antibody
    • IMP1 antibody
    • IMPAS antibody
    • IMPAS-1 antibody
    • Intramembrane protease 1 antibody
    • Intramembrane protease antibody
    • Minor histocompatibility antigen 13 antibody
    • Minor histocompatibility antigen H13 antibody
    • MSTP086 antibody
    • OTTHUMP00000030527 antibody
    • OTTHUMP00000030528 antibody
    • OTTHUMP00000030530 antibody
    • OTTHUMP00000214528 antibody
    • Presenilin-like protein 3 antibody
    • PSENL3 antibody
    • PSL3 antibody
    • Signal peptide peptidase antibody
    • Signal peptide peptidase beta antibody
    • SPP antibody
    see all

Anti-Signal Peptide Peptidase antibody 画像

  • Anti-Signal Peptide Peptidase antibody (ab113872) at 1 µg/ml + Mouse spleen lysate at 10 µg

    Predicted band size : 41 kDa

Anti-Signal Peptide Peptidase antibody (ab113872) 使用論文

ab113872 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"