製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SIGLECL1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 183-374 of Human SIGLECL1.

  • ポジティブ・コントロール
    • MCF7 whole cell lysate; NT2D1, IMR32 and U87-MG cell lysates

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 65 kDa.

ターゲット情報

  • 機能
    Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
  • 組織特異性
    Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal chord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow; it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis.
  • 配列類似性
    Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • ドメイン
    Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ38600 antibody
    • S2V antibody
    • sialic acid binding Ig-like lectin 12 (gene/pseudogene) antibody
    • Sialic acid-binding Ig-like lectin 12 antibody
    • Sialic acid-binding Ig-like lectin-like 1 antibody
    • Sialic acid-binding immunoglobulin-like lectins antibody
    • SIG12_HUMAN antibody
    • Siglec-12 antibody
    • Siglec-L1 antibody
    • SIGLEC-like 1 antibody
    • SIGLEC-like gene antibody
    • SIGLEC-like protein 1 antibody
    • Siglec-XII antibody
    • Siglec12 antibody
    • SLG antibody
    see all

画像

  • Anti-SIGLECL1 antibody (ab106537) at 1/2000 dilution + MCF7 whole cell lysate at 30 µg

    Predicted band size : 65 kDa

プロトコール

参考文献

ab106537 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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