Anti-Sialyl Tn 抗体 [STn 219], prediluted (ab76755)

製品の概要

  • 製品名
    Anti-Sialyl Tn antibody [STn 219], prediluted
    Sialyl Tn 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [STn 219] to Sialyl Tn, prediluted
  • アプリケーション
    適用あり: IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Sheep, Human
  • 免疫原

    Ovine submaxillary mucin (OSM)

  • エピトープ
    NeuAc alpha GalNacOSer/Thr
  • ポジティブ・コントロール
    • Human gastrointestinal tumor, prostate and ovary carcinomas.
  • 特記事項

    This product was changed from ascites to tissue culture supernatant on 15th June 2017.  Lot numbers higher than GR225970-2 will be from tissue culture supernatant.  Please note that the dilutions may need to be adjusted accordingly.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab76755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
IHC-Fr
  • 追加情報
    IHC-P: Ready to use.
    IHC-Fr: Ready to use.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性
      Sialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers including breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase: ST6GalNAc I, which catalyzes the transfer of a sialic acid residue in alpha2,6-linkage to the GalNAcalpha1-O-Ser/Thr structure. The resulting disaccharide (Neu5Acalpha2-6GalNAcalpha1-O-Ser/Thr) cannot be further elongated and sialyl-Tn expression results therefore in a shortening of the O-glycan chains
    • 別名
      • CD175s antibody
      • Sialosyl Tn antibody
      • sTn antibody

    プロトコール

    参考文献

    ab76755 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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