製品の概要

  • 製品名
    Anti-SHPRH antibody [2994C1a]
    SHPRH 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2994C1a] to SHPRH
  • アプリケーション
    適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Recombinant fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment derived from the central region of Human SHPRH

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 193 kDa.
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能
    E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
  • 組織特異性
    Broadly expressed.
  • パスウェイ
    Protein modification; protein ubiquitination.
  • 配列類似性
    Belongs to the SNF2/RAD54 helicase family.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    Contains 1 PHD-type zinc finger.
    Contains 1 RING-type zinc finger.
  • ドメイン
    The RING finger mediates E3 ubiquitin ligase activity.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bA545I5.2 antibody
    • E3 ubiquitin-protein ligase SHPRH antibody
    • FLJ27258 antibody
    • FLJ37625 antibody
    • FLJ45012 antibody
    • FLJ90837 antibody
    • histone-linker antibody
    • KIAA2023 antibody
    • MGC134886 antibody
    • PHD and RING finger domain-containing helicase antibody
    • Shprh antibody
    • SHPRH_HUMAN antibody
    • SNF2 antibody
    • SNF2 histone linker PHD RING helicase antibody
    see all

画像

  • Anti-SHPRH antibody [2994C1a] (ab84856) + immunogen (recombinant fragment of Human SHPRH)

    Predicted band size : 193 kDa

プロトコール

参考文献

ab84856 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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