製品の概要

  • 製品名Anti-SHP1 (phospho Y564) antibody
    SHP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SHP1 (phospho Y564)
  • 特異性ab79294 detects endogenous levels of SHP1 only when phosphorylated at tyrosine 564.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Syntheticphosphopeptide derived from human SHP1 around the phosphorylation site of tyrosine 564 (DVYPEN).

  • ポジティブ・コントロール
    • Extracts from COS7 cells, treated with EGF (200ng/ml, 30mins)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab79294 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 68 kDa.
ELISA 1/10000.

ターゲット情報

  • 機能Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.
  • 組織特異性Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.
  • 配列類似性Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
    Contains 2 SH2 domains.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻訳後修飾Phosphorylated on serine and tyrosine residues.
  • 細胞内局在Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 70Z-SHP antibody
    • EC 3.1.3.48 antibody
    • HCP antibody
    • HCPH antibody
    • Hematopoietic cell phosphatase antibody
    • Hematopoietic cell protein tyrosine phosphatase antibody
    • Hematopoietic cell protein-tyrosine phosphatase antibody
    • HPTP1C antibody
    • Protein tyrosine phosphatase 1C antibody
    • Protein tyrosine phosphatase non receptor type 6 antibody
    • Protein tyrosine phosphatase SHP1 antibody
    • Protein-tyrosine phosphatase 1C antibody
    • protein-tyrosine phosphatase SHP 1 antibody
    • Protein-tyrosine phosphatase SHP-1 antibody
    • PTN6_HUMAN antibody
    • PTP 1C antibody
    • PTP-1C antibody
    • PTP1C antibody
    • Ptpn6 antibody
    • SH PTP 1 antibody
    • SH PTP1 antibody
    • SH-PTP1 antibody
    • SHP 1 antibody
    • SHP 1L antibody
    • SHP1 antibody
    • SHP1L antibody
    • tyrosine protein phosphatase non receptor type 6 antibody
    • Tyrosine-protein phosphatase non-receptor type 6 antibody
    see all

Anti-SHP1 (phospho Y564) antibody 画像

  • All lanes : Anti-SHP1 (phospho Y564) antibody (ab79294) at 1/1000 dilution

    Lane 1 : extracts from COS7 cells, treated with EGF (200 ng/ml, 30 mins)
    Lane 2 : extracts from COS7 cells, treated with EGF (200 ng/ml, 30 mins) with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 68 kDa

Anti-SHP1 (phospho Y564) antibody (ab79294) 使用論文

ab79294 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab79294.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"