Anti-SHP1 (phospho Y564) 抗体 (ab79294)
Key features and details
- Rabbit polyclonal to SHP1 (phospho Y564)
- Suitable for: WB
- Reacts with: African green monkey
- Isotype: IgG
製品の概要
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製品名
Anti-SHP1 (phospho Y564) antibody
SHP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SHP1 (phospho Y564) -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: African green monkey -
免疫原
Synthetic peptide corresponding to Human SHP1 (phospho Y564).
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ポジティブ・コントロール
- Extracts from COS7 cells, treated with EGF (200ng/ml, 30mins)
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab79294 is purified from rabbit antiserum by chromatography using an epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab79294の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 68 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Predicted molecular weight: 68 kDa. |
ターゲット情報
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機能
Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. -
組織特異性
Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells. -
配列類似性
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
Contains 2 SH2 domains.
Contains 1 tyrosine-protein phosphatase domain. -
翻訳後修飾
Phosphorylated on serine and tyrosine residues. -
細胞内局在
Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II. - Information by UniProt
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別名
- 70Z-SHP antibody
- EC 3.1.3.48 antibody
- HCP antibody
see all
画像
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All lanes : Anti-SHP1 (phospho Y564) antibody (ab79294) at 1/1000 dilution
Lane 1 : extracts from COS7 cells, treated with EGF (200 ng/ml, 30 mins)
Lane 2 : extracts from COS7 cells, treated with EGF (200 ng/ml, 30 mins) with immunising peptide at 10 µg
Lysates/proteins at 30 µg per lane.
Predicted band size: 68 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab79294 は論文での使用が確認できていません。