製品の概要

  • 製品名Anti-SHC4 (phospho) antibody
    SHC4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SHC4 (phospho)
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment containing a sequence corresponding to a region within amino acids 352-609 of Human SHC4 (NP_976224).

  • ポジティブ・コントロール
    • MOLT4 whole cell lysate; A431 lysate

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Store in the dark. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 69 kDa.

ターゲット情報

  • 機能Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
  • 組織特異性Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive potential.
  • 配列類似性Contains 1 PID domain.
    Contains 1 SH2 domain.
  • 翻訳後修飾Phosphorylated; the phosphorylation is enhanced by EGF. Phosphorylation at Tyr-424 is required for the interaction with GRB2.
  • 細胞内局在Cell junction > synapse > postsynaptic cell membrane. Colocalized with MUSK at the neuromuscular junction.
  • Information by UniProt
  • 参照データベース
  • 別名
    • hShcD antibody
    • MGC34023 antibody
    • Rai like protein antibody
    • Rai-like protein antibody
    • RaLP antibody
    • SH2 domain protein C4 antibody
    • SHC (Src homology 2 domain containing) family member 4 antibody
    • SHC 4 antibody
    • SHC antibody
    • SHC family member 4 antibody
    • SHC transforming protein 4 antibody
    • SHC transforming protein D antibody
    • SHC-transforming protein 4 antibody
    • SHC-transforming protein D antibody
    • Shc4 antibody
    • SHC4_HUMAN antibody
    • SHCD antibody
    • Src homology 2 domain containing family member 4 antibody
    • Src homology 2 domain containing transforming protein C4 antibody
    • Src homology 2 domain-containing-transforming protein C4 antibody
    see all

Anti-SHC4 (phospho) antibody 画像

  • Anti-SHC4 (phospho) antibody (ab96182) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

    Predicted band size : 69 kDa

Anti-SHC4 (phospho) antibody (ab96182) 使用論文

ab96182 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96182.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"