製品の概要

  • 製品名Anti-SH3MD2 antibody
    SH3MD2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SH3MD2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide from within residues: LKLLSGASTK RKPRVSPPAS PTLEVELGSA ELPLQGAVGP ELPPGGGHGR, corresponding to internal sequence amino acids 720-769 of Human SH3MD2 (NP_065921).

  • ポジティブ・コントロール
    • DU145 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 93 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
  • 細胞内局在Golgi Apparatus. Lamellipodium. Perinuclear region of cytoplasm.
  • 参照データベース
  • 別名
    • FLJ21602 antibody
    • KIAA1494 antibody
    • Plenty of SH3 domains antibody
    • Plenty of SH3s antibody
    • POSH antibody
    • Ring finger protein 142 antibody
    • RNF 142 antibody
    • RNF142 antibody
    • SH3 domain containing ring finger 1 antibody
    • SH3 domain containing RING finger protein 1 antibody
    • SH3 multiple domains 2 antibody
    • SH3RF1 antibody
    see all

Anti-SH3MD2 antibody 画像

  • Anti-SH3MD2 antibody (ab90180) at 1 µg/ml + DU145 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 93 kDa

Anti-SH3MD2 antibody (ab90180) 使用論文

ab90180 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab90180.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"