製品の概要

  • 製品名Anti-SH3BP4 antibody
    SH3BP4 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SH3BP4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-110 of Human SH3BP4

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Functions in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis.
    • 組織特異性Expressed in all tissues tested with higher expression in pancreas. Expressed by retinal pigment epithelial cells (at protein level).
    • 配列類似性Contains 1 SH3 domain.
    • ドメインThe SH3 domain mediates localization to the clathrin-coated pits and vesicles. The SH3 domain mediates interaction with DNM2 and the cytoplasmic part of TFRC with a lower affinity.
    • 翻訳後修飾Phosphorylated upon EGF stimulation. Phosphorylation prevents interaction with DNM2.
    • 細胞内局在Membrane > clathrin-coated pit. Cytoplasmic vesicle > clathrin-coated vesicle. Nucleus. Specifically associated with transferrin receptor-containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BOG25 antibody
      • EH binding protein antibody
      • EH binding protein 10 antibody
      • EH-binding protein 10 antibody
      • EHB10 antibody
      • SH3 domain binding protein 4 antibody
      • SH3 domain-binding protein 4 antibody
      • SH3B4_HUMAN antibody
      • sh3bp4 antibody
      • Transferrin receptor trafficking protein antibody
      • Transferrin receptor-trafficking protein antibody
      • TTP antibody
      see all

    Anti-SH3BP4 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57005 SH3BP4 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-SH3BP4 antibody (ab57005) 使用論文

    ab57005 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting Abcam regarding our SH3BP4 antibodies.


    Regarding ab106609, this antibody is specific for isoform 1.


    The immunogen of antibody ab57005 shares 97% identity with the mouse and rat sequences, thus it is ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"