製品の概要

  • 製品名Anti-SH3BP4 antibody
    SH3BP4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SH3BP4
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to 18 amino acids near the C terminal end of Human SH3BP4 (NP_055336).

  • ポジティブ・コントロール
    • Rat lung tissue lysate. Human lung tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab106609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 107 kDa.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能Functions in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis.
  • 組織特異性Expressed in all tissues tested with higher expression in pancreas. Expressed by retinal pigment epithelial cells (at protein level).
  • 配列類似性Contains 1 SH3 domain.
  • ドメインThe SH3 domain mediates localization to the clathrin-coated pits and vesicles. The SH3 domain mediates interaction with DNM2 and the cytoplasmic part of TFRC with a lower affinity.
  • 翻訳後修飾Phosphorylated upon EGF stimulation. Phosphorylation prevents interaction with DNM2.
  • 細胞内局在Membrane > clathrin-coated pit. Cytoplasmic vesicle > clathrin-coated vesicle. Nucleus. Specifically associated with transferrin receptor-containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BOG25 antibody
    • EH binding protein antibody
    • EH binding protein 10 antibody
    • EH-binding protein 10 antibody
    • EHB10 antibody
    • SH3 domain binding protein 4 antibody
    • SH3 domain-binding protein 4 antibody
    • SH3B4_HUMAN antibody
    • sh3bp4 antibody
    • Transferrin receptor trafficking protein antibody
    • Transferrin receptor-trafficking protein antibody
    • TTP antibody
    see all

Anti-SH3BP4 antibody 画像

  • Lane 1 : Anti-SH3BP4 antibody (ab106609) at 1 µg/ml
    Lane 2 : Anti-SH3BP4 antibody (ab106609) at 2 µg/ml

    Lane 1 : Rat lung tissue lysate
    Lane 2 : Rat lung tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 107 kDa
  • ab106609, at 5µg/ml, staining SH3BP4 in paraffin embedded Human lung tissue by Immunohistochemistry.

Anti-SH3BP4 antibody (ab106609) 使用論文

ab106609 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam regarding our SH3BP4 antibodies.


Regarding ab106609, this antibody is specific for isoform 1.


The immunogen of antibody ab57005 shares 97% identity with the mouse and rat sequences, thus it is ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"