製品の概要

  • 製品名Anti-SH3BP2 antibody
    SH3BP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SH3BP2
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 150-200 of Human SH3BP2 (NP_001116153.1).

  • ポジティブ・コントロール
    • HeLa whole cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab117767 was affinity purified using an epitope specific to SH3BP2 immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab117767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 62 kDa.
IP Use at 2-10 µg/mg of lysate.

ターゲット情報

  • 機能Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
  • 組織特異性Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas.
  • 関連疾患Defects in SH3BP2 are the cause of cherubism (CRBM) [MIM:118400]. CRBM is an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws, which often begins around three years of age. It is followed by development of fibrous tissue masses, which causes a characteristic facial swelling.
  • 配列類似性Contains 1 PH domain.
    Contains 1 SH2 domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3BP-2 antibody
    • 3BP2 antibody
    • 3BP2_HUMAN antibody
    • Abl SH3 binding protein 2 antibody
    • Cherubism antibody
    • CRBM antibody
    • CRPM antibody
    • FLJ42079 antibody
    • FLJ54978 antibody
    • RES4-23 antibody
    • SH3 domain binding protein 2 antibody
    • SH3 domain-binding protein 2 antibody
    • Sh3bp2 antibody
    • TNFAIP3 interacting protein 2 antibody
    see all

Anti-SH3BP2 antibody 画像

  • All lanes : Anti-SH3BP2 antibody (ab117767) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg

    Developed using the ECL technique

    Predicted band size : 62 kDa


    Exposure time : 3 minutes
  • Detection of SH3BP2 by Western Blot of Immunprecipitate.
    ab117767 at 1µg/ml staining SH3BP2 in HeLa whole cell lysate immunoprecipitated using ab117767 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 10 seconds.

Anti-SH3BP2 antibody (ab117767) 使用論文

ab117767 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"