製品の概要

  • 製品名Anti-SH2D4A antibody
    SH2D4A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SH2D4A
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-454 of Human SH2D4A (NP_071354.2).

  • ポジティブ・コントロール
    • Human pancreas and SH2D4A transfected 293T cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 53 kDa.
IHC-P 1/200. PubMed: 24315626

ターゲット情報

  • 機能Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
  • 組織特異性Ubiquitously expressed. Aberrantly expressed in some cancers.
  • 配列類似性Contains 1 SH2 domain.
  • 細胞内局在Cytoplasm. Located at podocyte foot processes.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ20967 antibody
    • PPP1R38 antibody
    • Protein phosphatase 1 regulatory subunit 38 antibody
    • Protein SH antibody
    • Protein SH(2)A antibody
    • Protein SH2A antibody
    • SH2 domain containing 4A antibody
    • SH2 domain containing protein 4A antibody
    • SH2 domain-containing protein 4A antibody
    • SH24A_HUMAN antibody
    • SH2A antibody
    • Sh2d4a antibody
    see all

Anti-SH2D4A antibody 画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of normal liver (left) and hepatocellular carcinoma (right) labelling SH2D4A with ab103166 at 1/200. Magnification: 400X. Representative pictures of different protein levels for SH2D4A.

  • Anti-SH2D4A antibody (ab103166) at 1/500 dilution + Human pancreas tissue lysate at 50 µg

    Predicted band size : 53 kDa
  • All lanes : Anti-SH2D4A antibody (ab103166) at 1/500 dilution

    Lane 1 : SH2D4A transfected 293T cell line lysate
    Lane 2 : Non transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 53 kDa

Anti-SH2D4A antibody (ab103166) 使用論文

This product has been referenced in:
  • Quagliata L  et al. SH2D4A is frequently downregulated in hepatocellular carcinoma and cirrhotic nodules. Eur J Cancer 50:731-8 (2014). IHC-P ; Human . Read more (PubMed: 24315626) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"