製品の概要

  • 製品名Anti-SGLT1 antibody
    SGLT1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SGLT1
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 550 - 650 of Mouse SGLT1.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Mouse Liver formalin fixed paraffin embedded tissue section.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab105755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
  • 組織特異性Expressed mainly in intestine and kidney.
  • 関連疾患Congenital glucose/galactose malabsorption
  • 配列類似性Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • 翻訳後修飾N-glycosylation is not necessary for the cotransporter function.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • D22S675 antibody
    • High affinity sodium glucose cotransporter 1 antibody
    • High affinity sodium glucose cotransporter antibody
    • High affinity sodium-glucose cotransporter antibody
    • Human Na+/glucose cotransporter 1 antibody
    • Na(+)/glucose cotransporter 1 antibody
    • Na+/glucose cotransporter 1 antibody
    • NAGT antibody
    • SC5A1_HUMAN antibody
    • SGLT 1 antibody
    • SGLT1 antibody
    • SLC5A1 antibody
    • Sodium glucose cotransporter 1 antibody
    • Sodium/glucose cotransporter 1 antibody
    • Solute carrier family 5 (sodium/glucose cotransporter) member 1 antibody
    • Solute carrier family 5 member 1 antibody
    see all

Anti-SGLT1 antibody 画像

  • IHC image of SGLT1 staining in Mouse Liver formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab105755, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-SGLT1 antibody (ab105755) 使用論文

ab105755 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"