Anti-SFRS4/SRSF4 抗体 (ab73893)
Key features and details
- Rabbit polyclonal to SFRS4/SRSF4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SFRS4/SRSF4 antibody
SFRS4/SRSF4 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SFRS4/SRSF4 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Synthetic peptide corresponding to Human SFRS4/SRSF4 (internal sequence).
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ポジティブ・コントロール
- Extracts from LoVo cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab73893の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 57 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Predicted molecular weight: 57 kDa. |
ターゲット情報
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機能
A probable role in alternative splice site selection during pre-mRNA splicing. -
配列類似性
Belongs to the splicing factor SR family.
Contains 2 RRM (RNA recognition motif) domains. -
翻訳後修飾
Extensively phosphorylated on serine residues in the RS domain. -
細胞内局在
Nucleus speckle. - Information by UniProt
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参照データベース
- Entrez Gene: 6429 Human
- Entrez Gene: 57317 Mouse
- Omim: 601940 Human
- SwissProt: Q08170 Human
- SwissProt: Q8VE97 Mouse
- Unigene: 469970 Human
- Unigene: 2478 Mouse
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別名
- arginine/serine-rich 4 antibody
- Pre mRNA splicing factor SRP75 antibody
- Pre-mRNA-splicing factor SRP75 antibody
see all
画像
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All lanes : Anti-SFRS4/SRSF4 antibody (ab73893) at 1/500 dilution
Lane 1 : extracts from LoVo cells
Lane 2 : extracts from LoVo cells with immunizing peptide at 5 µg
Lysates/proteins at 20 µg per lane.
Predicted band size: 57 kDa
Observed band size: 57 kDa
Additional bands at: 20 kDa, 48 kDa. We are unsure as to the identity of these extra bands.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab73893 は 3 報の論文で使用されています。
- Breitkopf SB et al. Serial-omics of P53-/-, Brca1-/- Mouse Breast Tumor and Normal Mammary Gland. Sci Rep 7:14503 (2017). PubMed: 29109428
- Guo H et al. Androgen receptor binding to an androgen-responsive element in the promoter of the Srsf4 gene inhibits its expression in mouse Sertoli cells. Mol Reprod Dev 82:976-85 (2015). PubMed: 26308373
- Gautrey HL & Tyson-Capper AJ Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells. PLoS One 7:e51497 (2012). WB ; Human . PubMed: 23284704