製品の概要

  • 製品名Anti-SF3A1 antibody
    SF3A1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SF3A1
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rabbit, Horse, Cow, Dog, Ferret, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between amino acids 300 and 350 of Human SF3A1 (NP_005868.1).

  • ポジティブ・コントロール
    • Human Anaplastic Thyroid Carcinoma, Bladder Cell Carcinoma, Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Small Cell Lung Cancer, Stomach Adenocarcinoma and Testicular Seminoma. Mouse Renal Cell Carcinoma and Teratoma.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84698 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
    • 組織特異性Ubiquitously expressed.
    • 配列類似性Contains 2 SURP motif repeats.
      Contains 1 ubiquitin-like domain.
    • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Pre mRNA processing 21 antibody
      • Pre mRNA splicing factor SF3a antibody
      • PRP21 antibody
      • PRPF21 antibody
      • SAP 114 antibody
      • SAP114 antibody
      • sf3a1 antibody
      • SF3A1_HUMAN antibody
      • SF3a120 antibody
      • Spliceosome associated protein 114 antibody
      • Spliceosome-associated protein 114 antibody
      • Splicing factor 3 subunit 1 antibody
      • Splicing factor 3a subunit 1 120kDa antibody
      • Splicing factor 3A subunit 1 antibody
      see all

    Anti-SF3A1 antibody 画像

    • ab84698, at 1/250 dilution, staining SF3A1 in formalin-fixed, paraffin-embedded human pancreatic islet cell tumor by Immunohistochemistry, using DAB staining.
    • ab84698, at 1/100 dilution, staining SF3A1 in formalin-fixed, paraffin-embedded mouse teratoma by Immunohistochemistry, using DAB staining.
    • ab84698, at 1/100 dilution, staining SF3A1 in formalin-fixed, paraffin-embedded human breast carcinoma by Immunohistochemistry using a Red fluorescent goat anti-rabbit IgG highly cross adsorbed Hilyte PlusTM 555 secondary antibody at a dilution of 1/100.

    Anti-SF3A1 antibody (ab84698) 使用論文

    ab84698 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab84698.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"