製品の概要

  • 製品名Anti-SETMAR antibody
    SETMAR 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SETMAR
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human SETMAR.

  • ポジティブ・コントロール
    • Human lung carcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA.
  • 組織特異性Widely expressed, with highest expression in placenta and ovary and lowest expression in skeletal muscle.
  • 配列類似性In the N-terminal section; belongs to the histone-lysine methyltransferase family.
    In the C-terminal section; belongs to the mariner transposase family.
    Contains 1 post-SET domain.
    Contains 1 pre-SET domain.
    Contains 1 SET domain.
  • ドメインThe mariner transposase Hsmar1 region mediates DNA-binding. It has no transposase activity because the active site contains an Asn in position 610 instead of a Asp residue.
  • 細胞内局在Nucleus. Chromosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Histone lysine N methyltransferase antibody
    • Histone lysine N methyltransferase SETMAR antibody
    • Hsmar 1 antibody
    • Hsmar1 antibody
    • Mariner transposase Hsmar1 antibody
    • Metnase antibody
    • SET domain and mariner transposase fusion antibody
    • SET domain and mariner transposase fusion gene antibody
    • SET domain and mariner transposase fusion gene containing protein antibody
    • SET domain and mariner transposase fusion gene-containing protein antibody
    • Setmar antibody
    • SETMR_HUMAN antibody
    see all

Anti-SETMAR antibody 画像

  • ab110909 at 1/50 dilution staining SETMAR in paraffin-embedded Human lung carcinoma tissue by Immunohistochemistry. The picture on the right is treated with the synthesized peptide.

Anti-SETMAR antibody (ab110909) 使用論文

ab110909 has not yet been referenced specifically in any publications.

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