製品の概要

  • 製品名Anti-SerpinB6 antibody
    SerpinB6 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to SerpinB6
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cynomolgus Monkey, Orangutan
  • 免疫原

    Synthetic peptide:

    NWDEQFDKENTEER

    (Human) from the internal region of the protein sequence according to NP_004559.4.

  • ポジティブ・コントロール
    • Human ovary lysates

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報Peptide ELISA: Antibody detection limit dilution 1/128000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
    • 組織特異性Expressed in keratinocytes (at protein level). Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. Expressed in the inner ear hair cells. Expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions.
    • 関連疾患Defects in SERPINB6 are the cause of deafness autosomal recessive type 91 (DFNB91) [MIM:613453]. It is a form of non-syndromic deafness characterized by progressive and age-dependent sensorineural hearing loss. Vestibular function is normal.
    • 配列類似性Belongs to the serpin family. Ov-serpin subfamily.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CAP antibody
      • Cytoplasmic antiproteinase antibody
      • Peptidase inhibitor 6 antibody
      • PI-6 antibody
      • PI6 antibody
      • Placental thrombin inhibitor antibody
      • Protease inhibitor 6 (placental thrombin inhibitor) antibody
      • PTI antibody
      • Serpin B6 antibody
      • SERPINB6 antibody
      • SPB6_HUMAN antibody
      see all

    Anti-SerpinB6 antibody 画像

    • Anti-SerpinB6 antibody (ab77372) at 0.1 µg/ml + human ovary lysate in RIPA buffer at 35 µg
      Developed using the ECL technique

      Predicted band size : 42 kDa
      Observed band size : 42 kDa

    Anti-SerpinB6 antibody (ab77372) 使用論文

    ab77372 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab77372.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"