Anti-Serotonin transporter 抗体 (ab102048)


  • 製品名
    Anti-Serotonin transporter antibody
    Serotonin transporter 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Serotonin transporter
  • 由来種
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-630 of Human Serotonin transporter (AAH69484.1).

  • ポジティブ・コントロール
    • Mouse lung lysate. Transfected 293T cell line.



Our Abpromise guarantee covers the use of ab102048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 71 kDa.


  • 機能
    Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
  • 組織特異性
    Expressed in platelets (at protein level).
  • 配列類似性
    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
  • 翻訳後修飾
    Glycosylated; modification with sialylated N-glycans is a requirement for transporters to associate with each other and to function as homooligomeric forms.
    Phosphorylated at Ser-611, Thr-613 and Thr-616.
  • 細胞内局在
    Cell membrane. Endomembrane system. Endosome membrane. Translocates from intracellular locations to the plasma membrane. Density of transporter molecules on the plasma membrane is itself regulated by serotonin.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5 HTT antibody
    • 5 HTTLPR antibody
    • 5 hydroxytryptamine (serotonin) transporter antibody
    • 5 hydroxytryptamine transporter antibody
    • 5HT transporter antibody
    • 5HTT antibody
    • hSERT antibody
    • HTT antibody
    • Na+/Cl- dependent serotonin transporter antibody
    • OCD1 antibody
    • SC6A4_HUMAN antibody
    • Serotonin transporter 1 antibody
    • SERT antibody
    • SERT1 antibody
    • Slc6a4 antibody
    • Sodium dependent serotonin transporter antibody
    • Sodium-dependent serotonin transporter antibody
    • Solute carrier family 6 (neurotransmitter transporter) member 4 antibody
    • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antibody
    • Solute carrier family 6 member 4 antibody
    see all


  • Anti-Serotonin transporter antibody (ab102048) at 1/500 dilution + Mouse lung tissue lysate at 50 µg

    Developed using the ECL technique.

    Predicted band size: 71 kDa

  • All lanes : Anti-Serotonin transporter antibody (ab102048) at 1/500 dilution

    Lane 1 : Serotonin transporter transfected lysate from 293T cell line
    Lane 2 : Non transfected lysate from 293T cell line

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 71 kDa
    Observed band size: 70.3 kDa (why is the actual band size different from the predicted?)



ab102048 has not yet been referenced specifically in any publications.

レビューと Q&A

Abcam has not validated the combination of species/application used in this Abreview.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Human Tissue sections (hct-116)
Antigen retrieval step
Yes - 0.1% TRITON IN PBS
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 0.5% · Temperature: R.T°C

Abcam user community

Verified customer

投稿 Nov 11 2016

Thanks for your enquiry.

I have looked into this question and it appears SERT is expressed in platelets. Perhaps this explains why you do not detect SERT in your macrophage and why samples that are found to express SERT are tissue extracts co...

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As long as the species and application are tested, you will get our Abpromise grantee over 180 days. that means in case the replacement doesn't work either, we'll refund you if you wish.

Please let me know about the alternative antibody of yo...

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Thank you for taking time to complete our questionnaire and for contacting us. I am sorry to hear this antibody is not providing satisfactory results.

The details provided will enable us to investigate this case and will provide us with vita...

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Thank you for contacting us.

I am sorry to hear you are experiencing difficulties with one of our products. We take product complaints very seriously, and investigate every product that we feel may not be performing correctly.

I a...

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Thank you for your reply.

The images show different band sizes since the samples are different. One image shows a band at 75kda (as predicted). This image was generated with endogenous protein from mouse lung tissue lysate.

The othe...

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Thank you for your inquiry.

We have one antibody that is tested and guaranteed for WB and human and mouse samples:

ab102048 (or use the following:

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Merci pour ces précisions.

Une suggestion que je n'ai pas mentionnée dans mon précédent email est d'essayer d'utiliser 5% de BSA comme agent bloquant à la place du lait. Pour certains anticorps la BSA permet...

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Merci de nous avoir contactés.

A notre connaissance, la réactivité contre les bivalves n'a pas encore été testée avec l'anticorps ab102048. Toutes les informations sur les cross-réactivit&eacut...

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