製品の概要

  • 製品名Anti-SERBP1 antibody
    SERBP1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SERBP1
  • アプリケーション適用あり: WB, ICC/IF, Flow Cytmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-403 of Human SERBP1

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 45 kDa.
ICC/IF Use a concentration of 10 µg/ml.
Flow Cyt Use 1µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
  • 組織特異性Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
  • 細胞内局在Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Also found in perinuclear regions.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CGI 55 antibody
    • CHD3IP antibody
    • Chromodomain helicase DNA binding protein 3 interacting protein antibody
    • DKFZp564M2423 antibody
    • FLJ90489 antibody
    • HABP4L antibody
    • PAI 1 mRNA binding protein antibody
    • PAI RBP1 antibody
    • PAI-RBP1 antibody
    • PAI1 RNA-binding protein 1 antibody
    • PAIRB_HUMAN antibody
    • PAIRBP1 antibody
    • Plasminogen activator inhibitor 1 RNA binding protein antibody
    • Plasminogen activator inhibitor 1 RNA-binding protein antibody
    • Serbp1 antibody
    • SERPINE1 mRNA binding protein 1 antibody
    • SERPINE1 mRNA-binding protein 1 antibody
    see all

Anti-SERBP1 antibody 画像

  • SERBP1 antibody (ab57285) used in immunofluorescence at 10ug/ml on HeLa cells.


  • Predicted band size : 45 kDa
    SERBP1 antibody (ab57285) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • Overlay histogram showing HEK293 cells stained with ab57285 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab57285, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in HEK293 cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-SERBP1 antibody (ab57285) 使用論文

This product has been referenced in:
  • Peluso JJ  et al. Plasminogen activator inhibitor 1 RNA-binding protein interacts with progesterone receptor membrane component 1 to regulate progesterone's ability to maintain the viability of spontaneously immortalized granulosa cells and rat granulosa cells. Biol Reprod 88:20 (2013). WB, ICC/IF ; Rat . Read more (PubMed: 23242527) »
  • Heberlein KR  et al. A novel mRNA binding protein complex promotes localized plasminogen activator inhibitor-1 accumulation at the myoendothelial junction. Arterioscler Thromb Vasc Biol 32:1271-9 (2012). ICC/IF ; Human . Read more (PubMed: 22383705) »

See all 3 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab57285.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"