製品の概要

  • 製品名
    Anti-Septin 11 antibody [998C6a]
    Septin 11 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [998C6a] to Septin 11
  • アプリケーション
    適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Recombinant fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment corresponsing to a region close to the N-terminus of Human Septin 11

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 49 kDa.
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
  • 組織特異性
    Widely expressed, except in leukocytes.
  • 関連疾患
    Note=A chromosomal aberration involving SEPT11 may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) with MLL/HRX.
  • 配列類似性
    Belongs to the septin family.
  • 細胞内局在
    Cytoplasm > cytoskeleton. Cell junction > synapse. Cell projection > dendritic spine. Cell projection > axon. Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.
  • Information by UniProt
  • 参照データベース
  • 別名
    • SEP11_HUMAN antibody
    • SEPT 11 antibody
    • Sept11 antibody
    • Septin-11 antibody
    • Septin11 antibody
    see all

画像

  • Anti-Septin 11 antibody [998C6a] (ab84858) + immunogen (recombinant fragment of Human protein)

    Predicted band size : 49 kDa

プロトコール

参考文献

ab84858 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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