製品の概要

  • 製品名Anti-SEPT6 antibody
    SEPT6 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to SEPT6
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cow, Dog
  • 免疫原

    Synthetic peptide:

    DEVNAFKQRKTA

    by a Cysteine residue linker, corresponding to C terminal amino acids 391-402 of Human SEPT6 (NP_665798.1; NP_055944.2; NP_665801.1).

  • ポジティブ・コントロール
    • Human testis, thyroid gland and MOLT4 cell lysates
  • 特記事項


    ab106924 is expected to recognize the reported isoforms NP_665798.1, NP_055944.2 and NP_665801.1. Reported variants NP_665799.1 and NP_665798.1 represent identical protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 一次抗体 備考ab106924 is expected to recognize the reported isoforms NP_665798.1, NP_055944.2 and NP_665801.1. Reported variants NP_665799.1 and NP_665798.1 represent identical protein.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 50 kDa.

ターゲット情報

  • 機能Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication.
  • 組織特異性Widely expressed.
  • 配列類似性Belongs to the septin family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm. Cytoplasm > cytoskeleton > spindle. Chromosome > centromere > kinetochore. Cleavage furrow. Midbody. In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KIAA0128 antibody
    • Nkrf antibody
    • RCG53214, isoform CRA_d antibody
    • RP5-876A24.2 antibody
    • SEP2 antibody
    • SEPT2 antibody
    • SEPT6 antibody
    • SEPT6/MLL FUSION GENE antibody
    • SEPT6_HUMAN antibody
    • Septin 2 antibody
    • Septin 6 antibody
    • Septin-6 antibody
    see all

Anti-SEPT6 antibody 画像

  • ab106944 (3.8µg/ml) staining of paraffin embedded Human Tonsil following Steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows specific staining in dividing cells just outside a germinal centre.

  • Anti-SEPT6 antibody (ab106944) at 1 µg/ml + Human testis lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 50 kDa

Anti-SEPT6 antibody (ab106944) 使用論文

ab106944 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106944.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"