製品の概要

  • 製品名Anti-SEPT4 antibody
    SEPT4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SEPT4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Human SEPT4 aa 247-266 conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    KNIQDNRVHCCLYFISPFGHG

  • ポジティブ・コントロール
    • Whole cell extract of HEK 293 cells transfected with ARTS expression plasmid.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab10441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/15000. Detects a band of approximately 32 kDa.

ターゲット情報

  • 機能Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
  • 組織特異性Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in platelets.
  • 配列類似性Belongs to the septin family.
  • 細胞内局在Cytoplasm. Cytoplasm > cytoskeleton. In platelets, found in areas surrounding alpha-granules and Mitochondrion. Nucleus. While predominantly localized in the mitochondria under resting conditions, isoform ARTS translocates into the nucleus after TGF-beta treatment and apoptosis induction.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Apoptosis-related protein in the TGF-beta signaling pathway antibody
    • ARTS antibody
    • Bradeion antibody
    • Bradeion beta antibody
    • Brain protein H5 antibody
    • CE5B3 antibody
    • CE5B3 beta antibody
    • Cell division control-related protein 2 antibody
    • Cerebral protein 7 antibody
    • H5 antibody
    • hCDCREL-2 antibody
    • hucep-7 antibody
    • MART antibody
    • Peanut-like protein 2 antibody
    • PNUTL2 antibody
    • SEP 4 antibody
    • SEP4 antibody
    • Sept4 antibody
    • SEPT4_HUMAN antibody
    • Septin M antibody
    • Septin-4 antibody
    see all

Anti-SEPT4 antibody (ab10441) 使用論文

ab10441 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"