製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SEPN1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 507-557 (NYFLDITSVK PEEIESNLFS FSSTFEDPST ATYMQFLKEG LRRGLPLLQP) of Human SEPN1 (NP_996809)

  • ポジティブ・コントロール
    • HepG2 Cell Lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, 1X PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab105943 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 組織特異性
    Isoform 1 and isoform 2 are expressed in skeletal muscle, brain, lung and placenta. Isoform 2 is also expressed in heart, diaphragm and stomach.
  • 関連疾患
    Defects in SEPN1 are the cause of myopathy SEPN1-related (M-SEPN1) [MIM:602771]. A group of neuromuscular disorders consisting of four nosological entities: classic multiminicore disease (MmD), rigid spine muscular dystrophy 1 syndrome (RSMD1), desmin-related myopathy with Mallory body-like inclusions (MB-DRM) and congenital fiber-type disproportion. All are clinically characterized by poor axial muscle strength, scoliosis and neck weakness, and a variable degree of spinal rigidity. Early ventilatory insufficiency can lead to death by respiratory failure.
  • 配列類似性
    Contains 1 EF-hand domain.
  • ドメイン
    The N-terminus (first 61 amino acids) contains an endoplasmic reticulum addressing and retention targeting signal.
  • 翻訳後修飾
    N-glycosylated (isoform 2).
  • 細胞内局在
    Endoplasmic reticulum membrane. Probably membrane-associated.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CFTD antibody
    • MDRS1 antibody
    • RSMD1 antibody
    • RSS antibody
    • Selenoprotein N antibody
    • Selenoprotein N, 1 antibody
    • SelN antibody
    • SELN_HUMAN antibody
    • sepn1 antibody
    see all

Anti-SEPN1 antibody 画像

  • Anti-SEPN1 antibody (ab105943) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 58 kDa

プロトコール

Anti-SEPN1 antibody (ab105943) 使用論文

ab105943 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab105943.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録