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RabMAb

Anti-SENP2 抗体 [EPR4356(2)] (ab124724)

製品の概要

  • 製品名
    Anti-SENP2 antibody [EPR4356(2)]
    SENP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4356(2)] to SENP2
  • アプリケーション
    適用あり: WB, IHC-P, ICC/IFmore details
    適用なし: Flow Cyt or IP
  • 種交差性
    交差種: Human
    非交差種: Mouse, Rat
  • 免疫原

    A synthetic peptide corresponding to residues in Human SENP2.

  • ポジティブ・コントロール
    • MDA-MB-435, NIH:OVCAR-3, and 293T cell lysates; Human colon tissue.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab124724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/10000 - 1/50000. Detects a band of approximately 68 kDa (predicted molecular weight: 68 kDa).
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF 1/250 - 1/500.
  • 追加情報
    Is unsuitable for Flow Cyt or IP.
  • ターゲット情報

    • 機能
      Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
    • 配列類似性
      Belongs to the peptidase C48 family.
    • ドメイン
      The N-terminus is necessary and sufficient for nuclear envelope targeting.
    • 翻訳後修飾
      Polyubiquitinated; which leads to proteasomal degradation.
    • 細胞内局在
      Nucleus > nuclear pore complex. Nucleus membrane. Cytoplasm. Shuttles between cytoplasm and nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Axam2 antibody
      • DKFZp762A2316 antibody
      • KIAA1331 antibody
      • Senp2 antibody
      • SENP2_HUMAN antibody
      • Sentrin specific protease 2 antibody
      • Sentrin-specific protease 2 antibody
      • Sentrin/SUMO specific protease SENP2 antibody
      • Sentrin/SUMO-specific protease SENP2 antibody
      • SMT3 specific isopeptidase 2 antibody
      • SMT3-specific isopeptidase 2 antibody
      • Smt3ip2 antibody
      • SUMO1/sentrin/SMT3 specific peptidase 2 antibody
      see all

    画像

    • ab124724, at 1/500 dilution, staining SENP2 in paraffin embedded Human colon tissue by immunohistochemistry.
    • All lanes : Anti-SENP2 antibody [EPR4356(2)] (ab124724) at 1/10000 dilution

      Lane 1 : MDA-MB-435 cell lysate
      Lane 2 : NIH:OVCAR-3 cell lysate
      Lane 3 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 68 kDa

    参考文献

    This product has been referenced in:

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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