製品の概要

  • 製品名Anti-SENP2 antibody
    SENP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SENP2
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Bat
  • 免疫原

    Synthetic peptide, corresponding to a region between residue 150 and 200 of Human SENP2 (NP_067640.2)

  • ポジティブ・コントロール
    • Whole cell lysate from HeLa or 293T cells

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab109590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 68 kDa.
IP Use at 2-5 µg/mg of lysate.

ターゲット情報

  • 機能Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
  • 配列類似性Belongs to the peptidase C48 family.
  • ドメインThe N-terminus is necessary and sufficient for nuclear envelope targeting.
  • 翻訳後修飾Polyubiquitinated; which leads to proteasomal degradation.
  • 細胞内局在Nucleus > nuclear pore complex. Nucleus membrane. Cytoplasm. Shuttles between cytoplasm and nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Axam2 antibody
    • DKFZp762A2316 antibody
    • KIAA1331 antibody
    • Senp2 antibody
    • SENP2_HUMAN antibody
    • Sentrin specific protease 2 antibody
    • Sentrin-specific protease 2 antibody
    • Sentrin/SUMO specific protease SENP2 antibody
    • Sentrin/SUMO-specific protease SENP2 antibody
    • SMT3 specific isopeptidase 2 antibody
    • SMT3-specific isopeptidase 2 antibody
    • Smt3ip2 antibody
    • SUMO1/sentrin/SMT3 specific peptidase 2 antibody
    see all

Anti-SENP2 antibody 画像

  • All lanes : Anti-SENP2 antibody (ab109590) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg
    Lane 4 : 293T whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 68 kDa


    Exposure time : 3 minutes
  • Detection of SENP2 by Western Blot of Immunprecipitate.
    ab109590 at 1µg/ml staining SENP2 in HeLa whole cell lysate immunoprecipitated using ab109590 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.

Anti-SENP2 antibody (ab109590) 使用論文

ab109590 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"