製品の概要

  • 製品名Anti-SEN1 antibody
  • 製品の詳細
    Rabbit polyclonal to SEN1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 186-235 (LAYTPLNEKS LALLLNYLHD FLKYLAKNSA TLFSASDYEV ALPEYHRKAV) of Human SEN1 (NP_006783).

  • ポジティブ・コントロール
    • Human fetal muscle lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84703 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to one of several complementation groups. SEN1 or MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B. It is capable of reversing the immortal phenotype of a subset of immortal cells. Overexpression of SEN1 in HeLa cells ultimately caused abnormal nuclear morphology and cell death.
  • 細胞内局在Nuclear
  • 参照データベース
  • 別名
    • Cell senescence related gene complementation group B antibody
    • Cellular senescence related protein 1 antibody
    • CSR antibody
    • CSRB antibody
    • MORF 4 antibody
    • MORF4 antibody
    • MORF4 protein antibody
    • Mortality factor 4 antibody
    • SEN 1 antibody
    • SEN antibody
    • Senescence (cellular) related 1 antibody
    • Senescence related cellular 1 antibody
    • Transcription factor like protein MORF4 antibody
    see all

Anti-SEN1 antibody 画像

  • Anti-SEN1 antibody (ab84703) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 27 kDa
    Observed band size : 29 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 20 kDa. We are unsure as to the identity of these extra bands.

Anti-SEN1 antibody (ab84703) 使用論文

ab84703 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"