製品の概要

製品の特性

ターゲット情報

  • 関連性
    Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
  • 細胞内局在
    Membrane; single-pass type I membrane protein
  • 参照データベース
  • 別名
    • SEMA5A antibody
    • SEMAF antibody
    • Semaphorin F antibody

参考文献

ab41484 has not yet been referenced specifically in any publications.

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