This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Anti-Semaphorin 3c 抗体 (ab39300)




  • 追加情報This antibody gave a positive result in ELISA against the immunizing peptide (ab39299).
    Not yet tested in other applications.

    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性The Semaphorins constitute a large family of secreted and membrane-tethered cell signaling molecules. They have functions in neural development, immunology, cardiac growth, vascular development, lung morphogenesis and axial bone patterning. Semaphorins are defined by the presence of a conserved Sema domain at the N-terminus. These proteins can be classified into eight classes depending on their structure and species origin. Classes 3 through 7 are found in vertebrates; class 3 are secreted, class 7 are GPI-anchored and class 4 through 6 are transmembrane proteins. Two distinct transmembrane receptor families have been identified as Semaphorin receptors. Neuropilins provide binding specificity for the class 3 Semaphorins, whereas Plexins, which also contain a Sema domain serve as signaling partners for class 3 Semaphorins and as functional receptors for transmembrane Semaphorins. Semaphorin 3c inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is expressed maximally between days E10-12 with moderate levels from day E13 until birth.
    • 細胞内局在Secreted
    • 参照データベース
    • 別名
      • Sema E antibody
      • SEMA3C antibody
      • semaE antibody
      • Semahorin3C antibody
      • Semaphorin E antibody
      • SemaphorinE antibody
      see all

    Anti-Semaphorin 3c antibody (ab39300) 使用論文

    ab39300 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 26°C
    Sample Mouse Cell (Neural Tube)
    Specification Neural Tube
    Permeabilization No
    Fixative IF-Paraformaldehyde/Paraffin embedded

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    投稿 Jun 13 2013

    Thank you for your patience.

    I spoke to my colleague Jill who is in charge to source new proteins, and even she agrees that we should have this protein in our catalog, I am afraid this will take quite a while ( more than two month at least). ...

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    Thank you for contacting us again.

    I think the problem with this peptide is that it will probably only be detected by the polyclonal. I cannot tell you if the monoclonal antibody can bind this peptide as the epitope wasn't mapped.


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    I am very pleased to hear you would like to accept our offer and test ab135167 Anti-Semaphorin 3c antibody [MM0607-29U11] in sELISA. This code will give you: 1 free primary antibody before the expiration date. To redeem this offer, plea...

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    Thank you for contacting us.

    Yes, that would be the way forward. Shall I send you the discount code, then?

    Looking forward to your reply.

    Use our products? Submit an Abreview. Earn rewards!

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    Thank you very much for your interest in our products.

    I am delighted to hear that you get on so well with this ab39300 Anti-Semaphorin 3c antibody. So far, as a fast track antibody, this product has only been tested in peptide ELISA, but not...

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