製品の概要

  • 製品名Anti-SELS antibody - Aminoterminal end
    SELS 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SELS - Aminoterminal end
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to N-terminal residues of human SELS

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab58656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
  • 細胞内局在Endoplasmic reticulum; endoplasmic reticulum membrane; single pass membrane protein.
  • 参照データベース
  • 別名
    • AD-015 antibody
    • ADO15 antibody
    • MGC104346 antibody
    • MGC2553 antibody
    • SBBI8 antibody
    • selenoprotein S antibody
    • SEPS1 antibody
    • VCP interacting membrane protein antibody
    • VCP-interacting membrane antibody
    • VIMP antibody
    see all

Anti-SELS antibody - Aminoterminal end (ab58656) 使用論文

This product has been referenced in:
  • Schoenmakers E  et al. Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest 120:4220-35 (2010). WB ; Human . Read more (PubMed: 21084748) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"