製品の概要

  • 製品名Anti-Selenoprotein M antibody [10C1]
    Selenoprotein M 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [10C1] to Selenoprotein M
  • アプリケーション適用あり: ELISA, WB, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human) purified from E coli

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.03% Sodium Azide
    Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名10C1
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab16960 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
IP
  • 追加情報ELISA: Use at an assay dependent dilution.
    IP: Use at a concentration of 1 - 2 µg/ml lysates.
    WB: 1/2000. Predicted molecular weight: 16 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Selenoprotein M is widely expressed and expressed highly in the mammalian brain. It is localized to the perinuclear structures (Golgi/ER). A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in antioxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange. The roles of Selenoprotein M have not been clearly identified until present time.
    • 細胞内局在Cytoplasm; perinuclear region. Endoplasmic reticulum Probable. Golgi apparatus Probable. Note: Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum.
    • 参照データベース
    • 別名
      • Selenoprotein M antibody
      • Selenoprotein SelM antibody
      • SELM antibody
      • SelM protein antibody
      • SEPM antibody
      see all

    Anti-Selenoprotein M antibody [10C1] (ab16960) 使用論文

    This product has been referenced in:
    • Xu G  et al. The relationship between deiodinase activity and inflammatory responses under the stimulation of uremic toxins. J Transl Med 12:239 (2014). WB ; Human . Read more (PubMed: 25174507) »
    • Goo JS  et al. Proteomic analysis of kidneys from selenoprotein M transgenic rats in response to increased bioability of selenium. Clin Proteomics 10:10 (2013). WB ; Rat . Read more (PubMed: 23937859) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"