製品の概要

  • 製品名
    Anti-SECISBP2 antibody [2957C2a]
    SECISBP2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2957C2a] to SECISBP2
  • アプリケーション
    適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment of human SECISBP2 derived from a near N terminal internal sequence.

  • ポジティブ・コントロール
    • HEK293 whole cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.2 - 2 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 95 kDa).
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
  • 組織特異性
    Expressed at high levels in testis.
  • 関連疾患
    Defects in SECISBP2 are a cause of abnormal thyroid hormone metabolism (ATHYHM) [MIM:609698]. This phenotype is associated with a reduction in type II iodothyronine deiodinase activity.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp686C09169 antibody
    • OTTHUMP00000064929 antibody
    • OTTHUMP00000064930 antibody
    • OTTHUMP00000064931 antibody
    • OTTHUMP00000064932 antibody
    • RP11 89K14.1 antibody
    • SBP 2 antibody
    • SBP2 antibody
    • SEBP2_HUMAN antibody
    • SECIS binding protein 2 antibody
    • SECIS-binding protein 2 antibody
    • SECISBP 2 antibody
    • SECISBP2 antibody
    • Selenocysteine insertion sequence binding protein 2 antibody
    • Selenocysteine insertion sequence-binding protein 2 antibody
    see all

画像

  • Anti-SECISBP2 antibody [2957C2a] (ab70601) at 2 µg/ml + HEK293 whole cell lysate at 25 µg
    Developed using the ECL technique

    Predicted band size : 95 kDa
    Observed band size : 105 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab70601 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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