Anti-SCYL2 抗体 (ab103819)
Key features and details
- Rabbit polyclonal to SCYL2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-SCYL2 antibody
SCYL2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SCYL2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human SCYL2 aa 1-950. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
-
ポジティブ・コントロール
- Jurkat cell line lysate. SCYL2 transfected 293T cell line lysate.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab103819の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 104 kDa.
|
特記事項 |
---|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 104 kDa. |
ターゲット情報
-
機能
Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521, has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system. -
配列類似性
Belongs to the protein kinase superfamily.
Contains 1 HEAT repeat.
Contains 1 protein kinase domain. -
翻訳後修飾
According to PubMed:15809293, autophosphorylated in presence of poly-L-lysine. -
細胞内局在
Cytoplasm > perinuclear region. Cytoplasmic vesicle > clathrin-coated vesicle. Golgi apparatus > trans-Golgi network membrane. Endosome membrane. According to PubMed:15809293, plasma membrane-associated in clathrin-coated vesicles. According to PubMed:16914521, colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes. - Information by UniProt
-
参照データベース
- Entrez Gene: 55681 Human
- Omim: 616365 Human
- SwissProt: Q6P3W7 Human
- Unigene: 506481 Human
-
別名
- AU015688 antibody
- AW536445 antibody
- BC030932 antibody
see all
画像
-
Anti-SCYL2 antibody (ab103819) at 1 µg/ml + Jurkat cell lysate at 50 µg
Predicted band size: 104 kDa -
All lanes : Anti-SCYL2 antibody (ab103819) at 1 µg/ml
Lane 1 : SCYL2 transfected 293T cell line lysate
Lane 2 : Non transfected 293T cell line lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 104 kDa
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab103819 は 1 報の論文で使用されています。
- Wojcechowskyj JA et al. Quantitative phosphoproteomics reveals extensive cellular reprogramming during HIV-1 entry. Cell Host Microbe 13:613-23 (2013). WB ; Human . PubMed: 23684312